Which consensus sequence is located at -10 in bacterial promoters?

The consensus sequence located at -10 in bacterial promoters is known as the Pribnow Box. This sequence is typically characterized by the presence of a conserved sequence that is crucial for the initiation of transcription in prokaryotic organisms. The Pribnow Box generally contains the consensus sequence TATAAT and is recognized by the RNA polymerase during the transcription process. This recognition facilitates the binding of the RNA polymerase to the promoter region and subsequent transcription of downstream genes.

In bacterial promoters, the -10 region is essential for the correct positioning of RNA polymerase, allowing it to unwind the DNA and start synthesizing RNA. The Pribnow Box is part of the larger promoter structure that includes the -35 region as well, where another set of sequences play a role in the recruitment of RNA polymerase, but the specific function of the Pribnow Box at -10 is critical for adequate transcription initiation.

Understanding the role of these sequences helps clarify the mechanisms of gene expression and regulation within bacterial systems.