University of Central Florida (UCF) PCB3063 Genetics Practice Final

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What components make up the eukaryotic initiation complex?

Large ribosomal subunit + mRNA

Small subunit + initiation factors + initiator tRNA

The eukaryotic initiation complex is crucial for the initiation of translation, and it consists specifically of the small ribosomal subunit, initiation factors, and the initiator tRNA.

The small ribosomal subunit binds to the mRNA at the start codon, while the various initiation factors help in assembling the complex and ensuring the proper arrangement of components for efficient translation initiation. The initiator tRNA, which carries the first amino acid (methionine in eukaryotes), pairs with the start codon on the mRNA, securing the correct first step in the polypeptide chain synthesis.

This combination of the small ribosomal subunit, initiation factors, and initiator tRNA effectively establishes the foundation for the ribosome's assembly and function in translation, making it the correct answer. Other options do not represent the complete or correct assembly of the components necessary for forming the eukaryotic initiation complex.

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Poly(A) tail + mRNA + small subunit

Repressor proteins + mRNA

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